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New once-daily sublingual formula combines eleuthero, coleus, maca root, African mango, guarana, Gymnema sylvestre, ginseng and chromium, with an ingredient-by-ingredient research overview
AURORA, Colo., Sept. 20, 2026 — Sugar Defender today announced the U.S. launch of its eight-ingredient daily liquid drop supplement formulated to support blood sugar and energy wellness in adults. The formula combines adaptogenic botanicals, an essential trace mineral, a fat-burning plant extract and a caffeine-containing natural stimulant in a sublingual liquid drop format, designed to be held under the tongue before swallowing for enhanced absorption. It is designed for adults who want a daily supplement that fits into an established routine of balanced nutrition, physical activity and regular healthcare.
The formula contains eleuthero (Eleutherococcus senticosus), coleus (Coleus forskohlii), maca root (Lepidium meyenii), African mango (Irvingia gabonensis), guarana (Paullinia cupana), Gymnema sylvestre, ginseng (Panax ginseng) and chromium. The recommended serving is two full droppers held under the tongue each morning before breakfast for 30 seconds before swallowing, or dissolved in water. All ingredient names are disclosed on the Supplement Facts label at sugardefender24.com; consumers are encouraged to review the full label before use. Sugar Defender is manufactured in the United States in an FDA-registered, GMP-certified facility using domestic and imported ingredients. The formula is plant-based, non-GMO and non-habit forming.
Alongside the launch, Sugar Defender is publishing an ingredient overview that summarizes published research on each component. The overview also explains where that research stops and what it does not establish about the finished product.
“Blood sugar and energy wellness supplements are often sold on bold promises built from loosely connected studies,” said Tom Green, Creator of Sugar Defender. “We took the opposite approach. Sugar Defender is a straightforward daily formula, and we’re telling consumers exactly what’s in it, what the science on each ingredient actually shows, and where the evidence is still limited.”
An Eight-Ingredient Formula for Daily Blood Sugar and Energy Wellness
Sugar Defender’s formula draws from four ingredient categories, each associated with different aspects of normal physiological function relevant to blood sugar and energy wellness:
- Adaptogenic botanicals: Eleuthero, maca root and ginseng contribute bioactive compounds with documented traditional use histories and research profiles in the context of normal stress response, normal energy metabolism and normal cognitive function.
- Metabolic and fat metabolism botanicals: Coleus and African mango contribute bioactive compounds studied in the context of normal fat metabolism, normal body composition support and normal metabolic function.
- Glucose metabolism support: Gymnema sylvestre and chromium contribute bioactive compounds and an essential trace mineral with established research profiles in the context of normal blood glucose markers and normal insulin sensitivity.
- Natural energy support: Guarana contributes naturally occurring caffeine and xanthines, studied in the context of normal energy levels and metabolic rate. Consumers should note that guarana is a source of caffeine and should consider their total daily caffeine intake from all sources.
The combination reflects the company’s view that blood sugar and energy wellness involves multiple interconnected systems — including normal glucose regulation, normal metabolic function, normal energy production and normal stress adaptation — rather than a single pathway. Sugar Defender emphasizes that this is a formulation rationale, not a clinical finding. The finished product has not been evaluated as a complete formula in published clinical trials.
Eleuthero: Research on Adaptogenic Activity and Normal Energy Metabolism
Eleuthero (Eleutherococcus senticosus), also known as Siberian ginseng, is a woody shrub native to Northeast Asia with a documented history of use in traditional Chinese and Russian medicine. Its bioactive compounds — eleutherosides — have been studied for their adaptogenic properties, including their relationship to normal stress response, normal energy metabolism and physical endurance support.
A study published in a peer-reviewed sports and exercise science journal examined eleuthero supplementation in adults over eight weeks and observed associations with improvements in endurance capacity and normal metabolic markers during sustained physical activity. These studies had important limits — specific standardized eleuthero preparations, defined populations, controlled conditions — and their findings describe how eleuthero interacts with energy and metabolic markers, not outcomes from the finished Sugar Defender formula. Its inclusion reflects eleuthero’s recognized adaptogenic research profile, not a product-specific clinical claim.
Coleus: Research on Normal Fat Metabolism and Body Composition
Coleus (Coleus forskohlii) root extract is standardized to contain forskolin — a diterpene compound that has attracted scientific interest for its relationship to normal cellular signaling through activation of adenylyl cyclase, an enzyme involved in normal fat metabolism and normal hormonal activity.
Research has examined coleus forskohlii extract in the context of normal body composition and normal fat metabolism markers in adult study populations. A systematic review noted associations between forskolin supplementation and changes in body composition markers in several studies, while noting the limited volume and variable methodological quality of available evidence. These studies had important limits and do not establish outcomes from the finished Sugar Defender formula. Its inclusion reflects the recognized research profile of forskolin in the context of normal metabolic function, not a product-specific clinical claim.
Maca Root: Research on Adaptogenic Activity and Normal Energy
Maca (Lepidium meyenii) is a root vegetable native to the Peruvian Andes, classified as an adaptogen. Its bioactive compounds — glucosinolates and macamides — have been studied for their relationship to normal energy, stamina and mood balance in adults.
A randomized, double-blind, placebo-controlled study examining maca root supplementation in adults observed associations with improvements in self-reported energy and mood markers compared with placebo. These studies had important limits — specific preparations, defined populations, short durations — and do not establish outcomes from the finished Sugar Defender formula. Its inclusion reflects maca’s recognized adaptogenic research profile, not a product-specific clinical claim.
African Mango: Research on Normal Body Weight and Metabolic Markers
African mango (Irvingia gabonensis) is a tree native to West and Central Africa whose seeds have been used in traditional cuisine and, more recently, studied in the context of normal body weight and metabolic markers.
A randomized, double-blind, placebo-controlled study published in the journal Lipids in Health and Disease examined Irvingia gabonensis seed extract supplementation in overweight adults over ten weeks and observed associations with improvements in body weight, waist circumference and certain metabolic markers compared with placebo. These studies had important limits — a specific seed extract preparation, a defined overweight population, controlled conditions — and their findings do not establish outcomes from the finished Sugar Defender formula. Its inclusion reflects the recognized research profile of African mango seed extract in the context of normal metabolic function, not a product-specific clinical claim.
Guarana: A Natural Source of Caffeine and Metabolic Xanthines
Guarana (Paullinia cupana) is a climbing plant native to the Amazon basin whose seeds are among the richest natural sources of caffeine, typically containing two to three times the caffeine concentration of coffee beans by weight. Guarana also contains theobromine, theophylline and antioxidant compounds, and has been studied in the context of normal energy levels, normal metabolic rate and cognitive function.
Research on guarana and caffeine has examined their relationship to normal energy expenditure and cognitive performance in adult populations. Consumers should be aware that guarana is a meaningful source of caffeine; individuals who are sensitive to caffeine, who consume other caffeinated products or who have been advised to limit caffeine intake should consult a qualified healthcare professional before use. These findings do not establish outcomes from the finished Sugar Defender formula. Its inclusion reflects guarana’s recognized research profile as a natural caffeine and xanthine source, not a product-specific clinical claim.
Gymnema Sylvestre: Research on Normal Blood Glucose and Insulin Sensitivity
Gymnema sylvestre is a climbing plant used for centuries in traditional Ayurvedic medicine. Its bioactive gymnemic acids have been studied for their relationship to normal glucose absorption in the intestinal tract and normal insulin sensitivity.
A number of small randomized controlled trials examining Gymnema sylvestre in adults with elevated blood glucose observed associations with improvements in fasting blood glucose and Hemoglobin A1C markers. A systematic review noted that while findings were generally encouraging, most trials were of short duration and modest sample size, limiting the strength of conclusions. These studies used specific preparations in defined populations and do not establish outcomes from the Sugar Defender formula. Individuals taking medication for blood glucose management should consult a qualified healthcare professional before use. Its inclusion reflects the recognized research profile of gymnemic acids in normal glucose metabolism, not a product-specific clinical claim.
Ginseng: Research on Normal Blood Glucose and Cognitive Function
Korean ginseng (Panax ginseng) root extract is a widely studied adaptogenic botanical. Its principal bioactive compounds — ginsenosides — have been examined in the context of normal blood glucose regulation, normal cognitive function and normal energy metabolism.
A systematic review of randomized controlled trials examining Korean ginseng supplementation in adults observed associations with improvements in fasting blood glucose markers and cognitive performance compared with placebo. These studies used specific standardized ginsenoside preparations in defined populations and do not establish outcomes from the Sugar Defender formula. Its inclusion reflects the recognized adaptogenic and metabolic research profile of Panax ginseng, not a product-specific clinical claim.
Chromium: A Trace Mineral Supporting Normal Glucose and Insulin Function
Chromium is an essential trace mineral recognized for its role in normal insulin function and the metabolism of carbohydrates, fats and proteins. A systematic review of chromium supplementation studies noted associations with improvements in glycaemic control markers in several adult study populations, with effects observed particularly in populations with insulin sensitivity concerns.
According to the National Institutes of Health Office of Dietary Supplements, chromium contributes to normal macronutrient metabolism and normal insulin activity. These studies used specific doses in defined populations and do not establish outcomes from the finished Sugar Defender formula. Its inclusion reflects chromium’s established nutritional role in normal glucose and insulin metabolism, not a product-specific clinical claim. Individuals taking medication for blood glucose management should consult a qualified healthcare professional before use.

What Ingredient Research Does and Does Not Show
Sugar Defender’s research overview separates three questions: what each ingredient is, what researchers have studied about it, and what has been demonstrated about the finished formula. Those questions have different answers.
The studies referenced here examined individual ingredients at specific doses, in specific populations and over specific periods. Sugar Defender combines eight ingredients in a daily sublingual serving, and the amounts, preparations and interactions within that formula differ from the conditions of any individual study. For that reason, Sugar Defender does not describe its formula as clinically proven and does not attribute ingredient-level research results to the finished product.
“We think consumers respond better to honesty than hype,” said Tom Green. “Every ingredient in Sugar Defender has a recognized nutritional role or an active research profile. What we won’t do is stretch a study beyond what it found.”
Safety and Suitability
Sugar Defender is intended for healthy adults. Individuals taking prescription medication — particularly those for blood glucose management, blood pressure or anticoagulation — should consult a qualified healthcare professional before use. Gymnema sylvestre and chromium have each been associated with potential interactions with glucose-lowering medications. Guarana is a source of naturally occurring caffeine; individuals sensitive to caffeine or those who have been advised to limit caffeine intake should consult a qualified healthcare professional before use and consider their total daily caffeine intake from all sources.
Sugar Defender is a dietary supplement and is not a substitute for prescribed diabetes medication, regular blood glucose monitoring or professional medical care. Individuals with diagnosed diabetes or pre-diabetes should consult a qualified healthcare professional before use and should not discontinue or adjust prescribed treatment in favour of dietary supplementation.
The same consultation applies to individuals who are pregnant, nursing, managing a medical condition, scheduled for surgery or taking other dietary supplements. The physical label and Supplement Facts panel at sugardefender24.com are the definitive source for all ingredient names, amounts, directions and warnings.
Product Format and Availability
Sugar Defender is available now to consumers across the United States through the company’s official website at sugardefender24.com. The recommended serving is two full droppers held under the tongue before breakfast, or dissolved in water. Manufactured in the United States in an FDA-registered, GMP-certified facility; plant-based, non-GMO and non-habit forming. All orders are backed by a 60-day money-back guarantee.
Under U.S. federal law, dietary supplements are not subject to pre-market FDA approval. GMP certification and FDA facility registration cover manufacturing process standards and quality controls and do not constitute endorsement of the product or its claims by the FDA.
About Sugar Defender
Sugar Defender was developed with the principle that blood sugar and energy wellness supplements should be formulated from ingredients with documented research histories, disclosed transparently on the label and represented accurately — without overstating what individual ingredient studies show about a finished multi-ingredient formula. The company’s mission is to offer adults a daily blood sugar and energy wellness option that draws on recognized botanical and nutritional research traditions, manufactured to verifiable quality standards and supported by honest communication about what the science does and does not establish. Every ingredient in Sugar Defender is selected on the basis of its published research profile or its recognized nutritional role.
Sugar Defender holds itself to three standards: complete ingredient disclosure on the Supplement Facts label, manufacturing in an FDA-registered, GMP-certified U.S. facility, and accurate representation of the science behind each component — including its limits. Sugar Defender’s formula combines eleuthero, coleus, maca root, African mango, guarana, Gymnema sylvestre, ginseng and chromium in a once-daily sublingual liquid drop. The formula is plant-based, non-GMO and non-habit forming. More information is available at sugardefender24.com.
References
- Kuo J, Chen KW, Cheng IS, et al. The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human. Chinese Journal of Physiology. 2010;53(2):105–111.
- Godard MP, Johnson BA, Richmond SR. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obesity Research. 2005;13(8):1335–1343.
- Gonzales GF, Córdova A, Vega K, et al. Acceptability, safety, and efficacy of oral administration of extracts of maca (Lepidium meyenii) in adult human subjects. Reproductive Biology and Endocrinology. 2006.
- Ngondi JL, Etoundi BC, Nyangono CB, et al. IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation. Lipids in Health and Disease. 2009;8:7.
- Haskell CF, Kennedy DO, Milne AL, et al. The effects of L-theanine, caffeine and their combination on cognition and mood. Biological Psychology. 2008;77(2):113–122.
- Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. Journal of Ethnopharmacology. 1990;30(3):295–300.
- Geng J, Dong J, Ni H, et al. Ginseng for cognition. Cochrane Database of Systematic Reviews. 2010;12:CD007769.
- Anderson RA. Chromium, glucose intolerance and diabetes. Journal of the American College of Nutrition. 1998;17(6):548–555.
Media Contact
Tom Green, Creator Sugar Defender
19655 E 35th Dr #100, Aurora, CO 80011, USA
Email: support@sugardefender.com
Phone: +1-866-994-8188
Website: sugardefender24.com
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Research cited in this release pertains to individual ingredients studied in isolation; it does not represent clinical evaluation of the Sugar Defender formula as a finished product, nor does it constitute endorsement by the referenced researchers, journals or institutions. Sugar Defender is not a substitute for prescribed diabetes medication or professional medical care.
The post Sugar Defender Reviews: Launches Eight-Ingredient Daily Liquid Drop Supplement for Blood Sugar and Energy Wellness in the U.S. appeared first on 24 Health Times.